Tuesday, May 30, 2017

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A polythene bag with an umbilical cord interface was used to keep premature lambs alive The lambs were kept stable for 4 weeks and showed signs of normal development An artificial womb resembling a plastic bag has been used to keep premature lambs alive for four weeks outside of their own mothers' wombs and could one day be applied to premature babies. The sealed bag, made of polythene, contains amniotic fluid to provide all the nutrients and protection needed for growth and an interface delivering oxygen just as an umbilical cord would, and exchanging gases just like a placenta. The next great medical innovations that could save children The system works to mimic the environment of a natural womb, and the team hopes to one day adapt the technology for use with premature babies. "We've developed a system that, as closely as possible, reproduces the environment of the womb and replaces the function of the placenta," said Dr. Alan Flake, a fetal surgeon and director of the Center for Fetal Research in the Center for Fetal Diagnosis and Treatment at Children's Hospital of Philadelphia who led the research, published Tuesday . "This, in theory, should allow support of premature infants," he said, adding that his team's goal is to "meet the unmet need of extreme prematurity." One in 10 US births is premature (younger than 37 weeks gestational age), according to the team. And about 30,000 per year are critically preterm, meaning they are born younger than 26 weeks. The average human gestation period is 40 weeks. Flake adds that this level of extreme prematurity is the leading cause of infant mortality and morbidity in the US, accounting for a third of all infant deaths and half of all cases of cerebral palsy attributed to prematurity. The Royal College of Obstetricians and Gynecologists in the UK also reports poor survival of babies born at gestations below 24 weeks, despite great progress in neonatal care. Globally, more than one in 10 pregnancies will end in preterm birth.

For the original version including any supplementary images or video, visit http://www.cnn.com/2017/04/26/health/artificial-womb-premature-babies-lambs/

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